Benzene

Benzene

SCHEMBL7901950

Cc1nccs1.c1ccccc1.c1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HSD17B10 Q99714 2/20 0.43
TSHR P16473 1/20 0.43
NOS1 P29475 1/20 0.43
FBP1 P09467 3/20 0.40
PDK1 Q15118 1/20 0.40
GRM5 P41594 1/20 0.39
CYP2A6 P11509 1/20 0.34
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
SLC11A2 P49281 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
PKM P14618 2/20 0.33
HTT P42858 2/20 0.33
PLA2G7 Q13093 1/20 0.33
AURKA O14965 1/20 0.33
PIM1 P11309 1/20 0.33
CDK2 P24941 1/20 0.33
GSK3B P49841 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5507 0.94
Water SCHEMBL9764760 0.92
Bromide SCHEMBL4988084 0.92
SCHEMBL28745257 0.92
Hydrogen Sulfide SCHEMBL27518477 0.92
Hydrochloric Acid SCHEMBL7267735 0.92
SCHEMBL10666861 0.92
Ammonia Solution, Strong SCHEMBL2911520 0.92
Hydrochloric Acid SCHEMBL20767879 0.89
Methyl Alcohol SCHEMBL475415 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6207464-B1 INCUBATING TARGET WITH DYE TO FORM A COVALENT BOND; BLUE FLUORESCING DYES CARNEGIE MELLON UNIVERSITY 2001-03-27 US disclosed
US-5852191-A Rigidized monomethine cyanines CARNEGIE MELLON UNIVERSITY (US) 1998-12-22 US disclosed