⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16067258 | 1.00 | — | — | |
| SCHEMBL13672987 | 1.00 | — | — | |
| SCHEMBL18286970 | 0.83 | — | — | |
| SCHEMBL3671823 | 0.81 | — | — | |
| SCHEMBL1054460 | 0.81 | — | — | |
| SCHEMBL21897929 | 0.79 | — | — | |
| SCHEMBL12323902 | 0.79 | KDM4E (0.35) | — | |
| SCHEMBL14138047 | 0.78 | — | — | |
| SCHEMBL12696634 | 0.77 | — | — | |
| SCHEMBL13569736 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2021118137-A1 | METHOD FOR ENZYMATICALLY PRODUCING BETA AMINO ACID USING NOVEL ESTER HYDROLASE | 건국대학교 산학협력단 | 2021-06-17 | — | — | WO | disclosed |
| US-20170281626-A1 | PYRIMIDINEDIONE COMPOUNDS | MyoKardia, Inc. | 2017-10-05 | — | — | US | disclosed |
| US-9540369-B2 | Use of kinase inhibitors to increase the susceptibility of gram positive bacteria to beta lactam antibiotics | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-01-10 | — | — | US | disclosed |
| US-20150307495-A1 | Use of Kinase Inhibitors to Increase the Susceptibility of Gram Positive Bacteria to Beta Lactam Antibiotics | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2015-10-29 | — | — | US | disclosed |
| WO-2010106081-A1 | PIPERIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-09-23 | — | — | WO | disclosed |
| EP-1692140-B1 | COMPOSITIONS USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMA (US) | 2009-12-09 | — | — | EP | disclosed |