Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138831 | 1.00 | TSHR (0.56) | TSHRMIFTDP1L3MBTL1PPARG | |
| SCHEMBL7138835 | 1.00 | TSHR (0.56) | TSHRMIFTDP1L3MBTL1PPARG | |
| SCHEMBL14967822 | 0.97 | TSHR (0.54) | TSHRMIFTDP1L3MBTL1PPARG | |
| SCHEMBL14967506 | 0.96 | TSHR (0.52) | TSHRMIFTDP1L3MBTL1PPARG | |
| SCHEMBL14968008 | 0.93 | TSHR (0.57) | TSHRALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL14967520 | 0.89 | TSHR (0.60) | TSHRTDP1L3MBTL1PPARGALDH1A1 | |
| SCHEMBL9092954 | 0.88 | TSHR (0.72) | TSHRTDP1L3MBTL1PPARGALDH1A1 | |
| SCHEMBL3890951 | 0.87 | TSHR (0.74) | TSHRALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL7143000 | 0.87 | TSHR (0.74) | TSHRALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL14967687 | 0.84 | TSHR (0.58) | TSHRTDP1L3MBTL1PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197953-B1 | ESTER INTERCHANGE, CRYSTALLIZATION, ISOMERIZATION; PREPARING 1,5-BENZOTHIAZEPINE DERIVATIVES | TANABE SEIYAKU CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| US-5998637-A | CRYSTALLIZATION; SEPARATION | TANABE SEIYAKU CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0861834-A1 | Process for preparing optically active trans-3-substituted glycidic acid ester | TANABE SEIYAKU CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |