Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.69 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.69 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.69 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.69 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 3/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.60 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907081 | 0.95 | F2 (0.68) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24766874 | 0.94 | F2 (0.66) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL4968230 | 0.94 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15216220 | 0.94 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19017236 | 0.94 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19751698 | 0.94 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL14503597 | 0.94 | F2 (0.62) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL20129535 | 0.93 | FOLH1 (0.67) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12578925 | 0.93 | F2 (0.68) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12650832 | 0.93 | F2 (0.68) | F2PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277489-B1 | Support for high performance affinity chromatography and other uses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-08-21 | — | — | US | disclosed |
| WO-2000032044-A1 | A NEW SUPPORT FOR HIGH PERFORMANCE AFFINITY CHROMATOGRAPHY AND OTHER USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-06-08 | — | — | WO | disclosed |