Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 14/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17241456 | 1.00 | TYMP (0.46) | TYMPSLC6A2ADORA1 | |
| SCHEMBL16581526 | 1.00 | TYMP (0.46) | TYMPSLC6A2ADORA1 | |
| SCHEMBL9800966 | 0.83 | SLC6A2 (0.41) | TYMPSLC6A2 | |
| SCHEMBL7235905 | 0.83 | TYMP (0.45) | TYMP | |
| SCHEMBL7235898 | 0.83 | TYMP (0.45) | TYMP | |
| SCHEMBL15513809 | 0.82 | TYMP (0.45) | TYMPSLC6A2 | |
| SCHEMBL11251475 | 0.82 | TYMP (0.45) | TYMPSLC6A2 | |
| SCHEMBL11251481 | 0.82 | TYMP (0.45) | TYMPSLC6A2 | |
| SCHEMBL2506638 | 0.82 | TYMP (0.43) | TYMPSLC6A2ADORA1 | |
| SCHEMBL3630083 | 0.81 | TYMP (0.48) | TYMPADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642799-B1 | Improved prodrugs for enzyme mediated activation | HOECHST AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| US-5621002-A | HAVING A MODIFIED COMPETITIVE ENZYME ACTIVITY INHBITOR LINKED TO A SPACER-DRUG; ENZYME CLEAVAGE AT A LOWER CONCENTRATION, I.E. LOW MICHAELIS-MENTEN CONSTANT(KM) | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| EP-0642799-A1 | Improved prodrugs for enzyme mediated activation | BEHRINGWERKE Aktiengesellschaft (DE) | 1995-03-15 | — | — | EP | disclosed |