SCHEMBL7903040

SCHEMBL7903040

COc1ccc(OCC2c3cc(O)c(O)cc3CCN2C(=O)c2cccc(Cl)c2)cc1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIN2C Q14957 4/20 0.84
GRIN2D O15399 1/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7901952 0.91 GRIN2C (1.00) GRIN2CGRIN2D
SCHEMBL7895807 0.91 GRIN2C (1.00) GRIN2CGRIN2D
SCHEMBL7901940 0.91 GRIN2C (1.00) GRIN2CGRIN2D
SCHEMBL7901341 0.87 GRIN2C (1.00) GRIN2CGRIN2D
SCHEMBL24049296 0.84 GRIN2C (0.76) GRIN2CGRIN2D
SCHEMBL7901990 0.84 GRIN2C (0.88) GRIN2CGRIN2D
SCHEMBL7899806 0.84 GRIN2C (0.86) GRIN2CGRIN2D
SCHEMBL7894792 0.83 GRIN2C (1.00) GRIN2CGRIN2D
SCHEMBL24049357 0.83 GRIN2C (0.75) GRIN2CGRIN2D
SCHEMBL24049372 0.83 GRIN2C (0.75) GRIN2CGRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010088414-A2 SUBUNIT SELECTIVE NMDA RECEPTOR POTENTIATORS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS EMORY UNIVERSITY (US) 2010-08-05 WO disclosed