Calcofluor White

Calcofluor White

SCHEMBL790333

O=S(=O)(O)c1cc(Nc2nc(Nc3ccccc3)nc(N(CCO)CCO)n2)ccc1C=Cc1ccc(Nc2nc(Nc3ccccc3)nc(N(CCO)CCO)n2)cc1S(=O)(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
CA9 Q16790 4/20 0.40
CA12 O43570 3/20 0.40
ENPP2 Q13822 1/20 0.39
RECQL P46063 1/20 0.39
MCL1 Q07820 1/20 0.39
KCNH3 Q9ULD8 6/20 0.39
SNCA P37840 1/20 0.38
RHOA P61586 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
TERT O14746 1/20 0.37
TNNI3 P19429 1/20 0.37
TNNT2 P45379 1/20 0.37
TNNC1 P63316 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
CCNE2 O96020 1/20 0.36
CCNE1 P24864 1/20 0.36
CDK2 P24941 1/20 0.36
RAD51 Q06609 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Calcofluor White SCHEMBL29352021 1.00 CA1 (0.40) CA1CA2CA9CA12ENPP2
Calcofluor White SCHEMBL790332 1.00 CA1 (0.40) CA1CA2CA9CA12ENPP2
Calcofluor White SCHEMBL29392658 1.00 CA1 (0.40) CA1CA2CA9CA12ENPP2
Calcofluor White SCHEMBL29353351 1.00 CA1 (0.40) CA1CA2CA9CA12ENPP2
Calcofluor White SCHEMBL5465530 0.99 CA1 (0.42) CA1CA2CA9CA12ENPP2
Calcofluor White SCHEMBL1235328 0.99 CA1 (0.40) CA1CA2CA9CA12ENPP2
Calcofluor White SCHEMBL30476488 0.99 CA1 (0.40) CA1CA2CA9CA12ENPP2
Calcofluor White SCHEMBL5465493 0.99 CA1 (0.40) CA1CA2CA9CA12ENPP2
Calcofluor White SCHEMBL11007078 0.99 CA1 (0.40) CA1CA2CA9CA12ENPP2
Calcofluor White SCHEMBL2220135 0.99 CA1 (0.40) CA1CA2CA9CA12ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457894-B2 Color-protecting detergent or cleaning agent having an optical brightener HENKEL AG & CO. KGAA (DE) 2019-10-29 US claimed
EP-2976415-B1 COLOUR PROTECTING DETERGENT COMPOPOSITION COMPRISING AN OPTICAL BRIGHTENER HENKEL AG & CO KGAA (DE) 2018-10-17 EP claimed
EP-2813572-B1 Improved techniques for transfecting protoplasts KEYGENE NV (NL) 2016-04-27 EP claimed
EP-2976415-A1 COLOR-PROTECTING DETERGENT OR CLEANING AGENT HAVING AN OPTICAL BRIGHTENER Henkel AG&Co. KGAA (DE) 2016-01-27 EP claimed
US-20160010030-A1 COLOR-PROTECTING DETERGENT OR CLEANING AGENT HAVING AN OPTICAL BRIGHTENER HENKEL AG & CO. KGAA (DE) 2016-01-14 US claimed
EP-2810051-A1 METHOD FOR DETERMINING THE CONCENTRATION OF BETA-D-GLUCAN Thermo Fisher Scientific Oy (FI) 2014-12-10 EP claimed
EP-2516652-B1 Improved techniques for transfecting protoplasts KEYGENE NV (NL) 2014-11-05 EP claimed
WO-2014146985-A1 COLOR-PROTECTING DETERGENT OR CLEANING AGENT HAVING AN OPTICAL BRIGHTENER HENKEL AG & CO. KGAA (DE) 2014-09-25 WO claimed
EP-2176392-B1 COLOR-SAFE DETERGENT OR CLEANING AGENT HAVING OPTICAL BRIGHTENER HENKEL AG & CO KGAA (DE) 2013-10-23 EP claimed
US-20130203173-A1 Method for determining the concentration of beta-D-glucan THERMO FISHER SCIENTIFIC OY (FI) 2013-08-08 US claimed
WO-2013114002-A1 METHOD FOR DETERMINING THE CONCENTRATION OF BETA-D-GLUCAN THERMO FISHER SCIENTIFIC OY (FI) 2013-08-08 WO claimed
EP-1555009-B1 Skin make-up composition OREAL (FR) 2010-07-14 EP claimed
US-20100144579-A1 Color-Safe Detergent or Cleaning Agent having Optical Brightener HENKEL AG & CO. KGAA (DE) 2010-06-10 US claimed
US-20080184495-A1 Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition L'OREAL S.A. (FR) 2008-08-07 US claimed
US-20050031559-A1 Mineral particles containing optical brightener for lightening the face skin; mixture of silica, hydroxyapatite particles and dyes of stilbene, or coumarin; foundation powders with concealing properties L'OREAL (FR) 2005-02-10 US claimed
US-4216111-A Stable dispersions of fluorescent whitening agents of the bis-triazinylaminostilbene group in free acid form and method of preparing same HICKSON & WELCH LIMITED (GB) 1980-08-05 US claimed
EP-4652254-A1 DETERGENT HAVING IMPROVED WASHING/CLEANING PERFORMANCE Henkel AG & Co. KGaA (DE) 2025-11-26 EP disclosed
US-20250236818-A1 HAIR REMOVAL BY MEANS OF DETERGENT/DETERGENT ADDITIVES CONTAINING ENZYMES HENKEL AG & CO. KGAA (DE) 2025-07-24 US disclosed
US-4090974-A Carpet cleaning composition FMC CORPORATION (US) 1978-05-23 US disclosed
US-4060496-A HALOGENATED HYDROCARBON, FATTY ACID, ALKANOLAMINE, GLYCOL ETHER, WATER BURNISHINE PRODUCTS INC. (US) 1977-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080184495-A1 Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition KRT18, VIM, CD44 CA1 1828/4885CA2 2651/4885CA9 873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.