Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2898595 | 0.93 | ELANE (0.57) | ELANECYP2C9CYP3A4 | |
| SCHEMBL7901176 | 0.92 | ELANE (0.52) | ELANECYP2C9CYP3A4 | |
| SCHEMBL233309 | 0.92 | ELANE (0.67) | ELANECYP2C9CYP3A4 | |
| SCHEMBL232616 | 0.91 | ELANE (0.56) | ELANECYP2C9CYP3A4 | |
| SCHEMBL3797251 | 0.91 | ELANE (0.59) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2878932 | 0.90 | ELANE (0.55) | ELANECYP2C9CYP3A4 | |
| SCHEMBL230755 | 0.90 | ELANE (0.57) | ELANECYP2C9CYP3A4 | |
| SCHEMBL230833 | 0.90 | ELANE (0.59) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2742358 | 0.90 | ELANE (0.67) | ELANECYP2C9CYP3A4 | |
| SCHEMBL230892 | 0.90 | ELANE (0.55) | ELANECYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010078953-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-07-15 | — | — | WO | disclosed |