Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16656855 | 0.84 | TSHR (0.53) | POLBHPGDTSHR | |
| SCHEMBL11919305 | 0.83 | TSHR (0.56) | POLBKMT2ANPC1RAB9AHPGD | |
| SCHEMBL3901059 | 0.82 | POLB (0.54) | POLBKMT2ANPC1RAB9AHPGD | |
| SCHEMBL10265412 | 0.81 | PARP1 (0.51) | POLBTSHR | |
| SCHEMBL9971001 | 0.81 | CPS1 (0.56) | POLBKMT2ANPC1RAB9AHPGD | |
| SCHEMBL3901062 | 0.80 | POLB (0.55) | POLBKMT2ANPC1RAB9AHPGD | |
| SCHEMBL13905030 | 0.78 | HTT (0.57) | KMT2AHPGDALDH1A1TSHRMEN1 | |
| SCHEMBL24746174 | 0.78 | HPGD (0.64) | POLBKMT2AHPGDALDH1A1TSHR | |
| SCHEMBL300831 | 0.76 | HPGD (0.68) | KMT2ANPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL3902063 | 0.76 | POLB (0.65) | POLBKMT2AHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |