⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25081773 | 0.88 | — | — | |
| SCHEMBL25081764 | 0.81 | PIK3R1 (0.31) | — | |
| SCHEMBL15120340 | 0.77 | — | — | |
| SCHEMBL1106465 | 0.74 | GAA (0.34) | — | |
| SCHEMBL8379802 | 0.70 | — | — | |
| SCHEMBL10094964 | 0.69 | — | — | |
| SCHEMBL10952397 | 0.68 | — | — | |
| SCHEMBL23513077 | 0.67 | — | — | |
| SCHEMBL25636202 | 0.67 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL25081711 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390404-B1 | TRICYCLIC COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2021-07-21 | — | — | EP | disclosed |
| US-8637500-B2 | Aminopyridine and carboxypyridine compounds as phosphodiesterase 10 inhibitors | AMGEN INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130029970-A1 | CB Receptor Agonists | IRONWOOD PHARMACEUTICALS, INC (US) | 2013-01-31 | — | — | US | disclosed |
| US-20100160280-A1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2010-06-24 | — | — | US | disclosed |