SCHEMBL7903684

SCHEMBL7903684

COC(=O)C(CCSC)NC(=O)c1ccc(COCc2ccco2)cc1-c1ccccc1C

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.78
FNTB P49356 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7903687 1.00 FNTA (0.78) FNTAFNTB
SCHEMBL7906928 0.92 FNTA (0.68) FNTAFNTB
SCHEMBL7906924 0.92 FNTA (0.68) FNTAFNTB
SCHEMBL7907097 0.89 FNTA (0.76) FNTAFNTB
SCHEMBL7907098 0.89 FNTA (0.76) FNTAFNTB
SCHEMBL7907200 0.88 FNTA (0.75) FNTAFNTB
SCHEMBL7907201 0.88 FNTA (0.75) FNTAFNTB
SCHEMBL7903932 0.88 FNTA (0.72) FNTAFNTB
SCHEMBL7903934 0.88 FNTA (0.72) FNTAFNTB
SCHEMBL7905427 0.87 FNTA (0.74) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed