Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 13/20 | 0.71 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1947174 | 1.00 | F9 (0.71) | F9F10PRSS1KLK1KLK5 | |
| Hydrochloric Acid SCHEMBL1948474 | 0.99 | F9 (0.70) | F9F10PRSS1KLK1KLK5 | |
| SCHEMBL1945722 | 0.91 | F9 (0.75) | F9 | |
| Hydrochloric Acid SCHEMBL1947515 | 0.90 | F9 (0.73) | F9 | |
| SCHEMBL12545871 | 0.89 | F9 (0.75) | F9F10PRSS1 | |
| SCHEMBL12812976 | 0.89 | F9 (0.59) | F9 | |
| SCHEMBL1946983 | 0.88 | F9 (0.73) | F9KLK1KLK5 | |
| SCHEMBL1948965 | 0.87 | F9 (0.77) | F9F10PRSS1 | |
| SCHEMBL1947057 | 0.87 | F9 (0.79) | F9F10PRSS1 | |
| SCHEMBL1947691 | 0.87 | F9 (0.71) | F9F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373634-B1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARM CO LTD (JP) | 2015-11-11 | — | — | EP | disclosed |
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |