SCHEMBL7904071

SCHEMBL7904071

CSCCC(NC(=O)c1ccc(COCCCC2CCCCC2)cc1-c1ccccc1C)C(=O)O.[LiH]

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.70
FNTB P49356 2/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7907211 0.99 FNTA (0.70) FNTAFNTB
SCHEMBL7907207 0.99 FNTA (0.70) FNTAFNTB
Lithium SCHEMBL7904077 0.98 FNTA (0.70) FNTAFNTB
SCHEMBL7910616 0.96 FNTA (0.68) FNTAFNTB
SCHEMBL7910624 0.96 FNTA (0.68) FNTAFNTB
SCHEMBL7905468 0.95 FNTA (0.69) FNTAFNTB
SCHEMBL7905469 0.95 FNTA (0.69) FNTAFNTB
Lithium Ion SCHEMBL7904073 0.92 FNTA (0.64) FNTAFNTB
SCHEMBL7907010 0.91 FNTA (0.66) FNTAFNTB
SCHEMBL7907009 0.91 FNTA (0.66) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed
WO-1998050031-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 WO disclosed