Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6595313 | 0.91 | PDE5A (1.00) | PDE5APDE2A | |
| SCHEMBL6780463 | 0.91 | PDE5A (0.86) | PDE5APDE2A | |
| SCHEMBL7077541 | 0.90 | PDE5A (0.76) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6590189 | 0.90 | PDE5A (1.00) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6779227 | 0.90 | PDE5A (0.76) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6778630 | 0.90 | PDE5A (0.84) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6780204 | 0.89 | PDE5A (0.74) | PDE5APDE2A | |
| SCHEMBL1962546 | 0.88 | PDE5A (1.00) | PDE5APDE2A | |
| SCHEMBL6779758 | 0.87 | PDE5A (0.85) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL4219631 | 0.87 | PDE5A (1.00) | PDE5APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218392-B1 | FOR THERAPY AND PROPHYLAXIS OF ISCHEMIC HEART DISEASES SUCH AS ANGINA PECTORIS, MYOCARDIAL INFARCT AND CHRONIC AND ACUTE CARDIAC FAILURE, PULMONARY HYPERTENSION, ARTERIOSCLEROSIS AND BRONCHIAL ASTHMA | EISAI CO., LTD. (JP) | 2001-04-17 | — | — | US | claimed |
| US-6218392-B1 | FOR THERAPY AND PROPHYLAXIS OF ISCHEMIC HEART DISEASES SUCH AS ANGINA PECTORIS, MYOCARDIAL INFARCT AND CHRONIC AND ACUTE CARDIAC FAILURE, PULMONARY HYPERTENSION, ARTERIOSCLEROSIS AND BRONCHIAL ASTHMA | EISAI CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| US-5849741-A | Fused pyridazine compounds | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0722936-A1 | FUSED PYRIDAZINE COMPOUND | Eisai Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |