Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910920 | 1.00 | MEN1 (0.40) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL7905921 | 1.00 | MEN1 (0.40) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL7916922 | 0.92 | MEN1 (0.39) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL6714850 | 0.91 | MEN1 (0.44) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL13455405 | 0.91 | MEN1 (0.44) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL7911479 | 0.90 | MEN1 (0.39) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL8532791 | 0.87 | MEN1 (0.33) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL13455407 | 0.85 | MEN1 (0.39) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL6995482 | 0.84 | MEN1 (0.39) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL15136901 | 0.84 | KDM4C (0.43) | MEN1KMT2AKDM4CL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780644-A | BRANCHES AND CASCADES OF POLYOXYALKYLENE GLYCOLS; DRUG CARRIERS; CONTRAST AGENTS FOR MEDICAL IMAGING | DIBRA S.P.A. (IT) | 1998-07-14 | — | — | US | claimed |
| EP-0750649-B1 | BRANCHED POLYOXAALKYL MACROMOLECULES, PROCESS FOR MAKING THEM AND THEIR USES | BRACCO IMAGING SPA (IT) | 2001-12-19 | — | — | EP | disclosed |
| US-5780644-A | BRANCHES AND CASCADES OF POLYOXYALKYLENE GLYCOLS; DRUG CARRIERS; CONTRAST AGENTS FOR MEDICAL IMAGING | DIBRA S.P.A. (IT) | 1998-07-14 | — | — | US | disclosed |
| EP-0750649-A1 | BRANCHED POLYOXAALKYL MACROMOLECULES, PROCESS FOR MAKING THEM AND THEIR USES | BRACCO S.p.A. (IT) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995025763-A1 | BRANCHED POLYOXAALKYL MACROMOLECULES, PROCESS FOR MAKING THEM AND THEIR USES | BRACCO S.P.A. (IT) | 1995-09-28 | — | — | WO | disclosed |