SCHEMBL790458

SCHEMBL790458

Cc1[c]c(Cl)ncc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL352820 0.74
SCHEMBL351296 0.74
SCHEMBL3723008 0.70
SCHEMBL2371588 0.70
SCHEMBL29001795 0.70
SCHEMBL4926053 0.70
SCHEMBL12076718 0.70
SCHEMBL1045263 0.70
SCHEMBL4928793 0.70
SCHEMBL26933995 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024145505-A1 PYRIMIDINE CARBOXAMIDE COMPOUNDS ACRIVON THERAPEUTICS, INC. (US) 2024-07-04 WO claimed
CN-101103016-A Inhibitors of 11-beta hydroxyl steroid dehydrogenase type I and methods of using the same INCYTE CORP (US) 2008-01-09 CN claimed
WO-2024145505-A1 PYRIMIDINE CARBOXAMIDE COMPOUNDS ACRIVON THERAPEUTICS, INC. (US) 2024-07-04 WO disclosed
EP-2550264-B1 PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2016-06-08 EP disclosed
US-9040537-B2 Pyridazine compounds for controlling invertebrate pests BASF SE (DE) 2015-05-26 US disclosed
EP-2155194-B1 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO NEUROCRINE BIOSCIENCES INC (US) 2015-01-21 EP disclosed
EP-2763966-A1 INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES Syngenta Participations AG (CH) 2014-08-13 EP disclosed
EP-2615917-A2 PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS III BASF SE (DE) 2013-07-24 EP disclosed
US-20130180014-A1 Pyridine Compounds for Controlling Invertebrate Pests III BASF SE (DE) 2013-07-11 US disclosed
WO-2013050261-A1 INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2013-04-11 WO disclosed
EP-2550264-A1 PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2013-01-30 EP disclosed
WO-2006066818-A2 7-AMINO-6-HETARYL-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AND THE USE THEREOF FOR CONTROLLING PATHOGENIC FUNGI BASF AKTIENGESELLSCHAFT (DE) 2006-06-29 WO disclosed
WO-2006066799-A1 7-AMINO-6-HETEROARYL-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINES AND TO THE USE THEREOF FOR COMBATING PATHOGENIC FUNGI BASF AKTIENGESELLSCHAFT (DE) 2006-06-29 WO disclosed
US-6277790-B1 APPLYING PLANTS, SEEDS, SOILS OR ENVIRONMENT BASF AKTIENGESELLSCHAFT (DE) 2001-08-21 US disclosed
US-4853383-A β-blocking substituted imidazoles MERCK & CO., INC. (US) 1989-08-01 US disclosed
US-4642311-A β-adrenergic blocking imidazolylphenoxy propanolamines MERCK & CO., INC. (US) 1987-02-10 US disclosed
US-4567276-A HYPOTENSIVE AGENTS, ADRENERGIC BLOCKING AGENTS MERCK & CO., INC. (US) 1986-01-28 US disclosed
US-4440774-A ANTIHYPERTENSIVE AGENTS AND B-ANDRENERGIC BLOCKING AGENTS MERCK & CO., INC. (US) 1984-04-03 US disclosed
US-4199580-A HYPOTENSIVE AGENTS AND ADRENERGIC BLOCKING AGENTS MERCK & CO., INC. (US) 1980-04-22 US disclosed
US-4134983-A HYPOTENSIVE, ADRENERGIC BLOCKING AGENTS MERCK & CO., INC. (US) 1979-01-16 US disclosed