Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.42 |
| ▸ | FNTB | P49356 | 11/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903834 | 0.89 | FNTA (0.43) | FNTAFNTBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7904826 | 0.82 | FNTA (0.42) | FNTAFNTBFFAR1PPARGMYC | |
| SCHEMBL7904559 | 0.80 | MYC (0.43) | FNTAFNTBFFAR1TSHRNPC1 | |
| SCHEMBL7897722 | 0.80 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL7897724 | 0.80 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL7905242 | 0.79 | FNTA (0.63) | FNTAFNTB | |
| Lithium SCHEMBL7905243 | 0.79 | FNTA (0.63) | FNTAFNTB | |
| SCHEMBL7904816 | 0.79 | FFAR1 (0.42) | FNTAFNTBFFAR1PPARGMYC | |
| SCHEMBL7572010 | 0.79 | MYC (0.41) | FNTAFNTBFFAR1PPARGMYC | |
| SCHEMBL7897588 | 0.77 | FNTA (0.42) | FNTAFNTBFFAR1PPARGMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |