SCHEMBL7904871

SCHEMBL7904871

CSCCC(NC(=O)c1ccc(CO[C@H](COC(C)C)CC2CCCCC2)cc1-c1ccccc1C)C(=O)O.[LiH]

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.60
FNTB P49356 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7904878 1.00 FNTA (0.60) FNTAFNTB
SCHEMBL7904881 1.00 FNTA (0.60) FNTAFNTB
SCHEMBL7904020 0.99 FNTA (0.60) FNTAFNTB
SCHEMBL7904024 0.99 FNTA (0.60) FNTAFNTB
SCHEMBL7904016 0.99 FNTA (0.60) FNTAFNTB
SCHEMBL7910126 0.94 FNTA (0.64) FNTAFNTB
SCHEMBL7910117 0.94 FNTA (0.64) FNTAFNTB
SCHEMBL7897798 0.94 FNTA (0.60) FNTAFNTB
SCHEMBL7906070 0.94 FNTA (0.60) FNTAFNTB
SCHEMBL7906080 0.94 FNTA (0.60) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed