SCHEMBL7905068

SCHEMBL7905068

CCOCC(CC1CCCCC1)OCc1ccc(C(=O)N[C@@H](CCSC)C(=O)O)c(-c2ccccc2C)c1.[LiH]

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.63
FNTB P49356 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7905064 1.00 FNTA (0.63) FNTAFNTB
SCHEMBL7906537 0.99 FNTA (0.64) FNTAFNTB
SCHEMBL7906533 0.99 FNTA (0.64) FNTAFNTB
SCHEMBL7907307 0.94 FNTA (0.65) FNTAFNTB
SCHEMBL7910038 0.94 FNTA (0.63) FNTAFNTB
SCHEMBL7910047 0.94 FNTA (0.63) FNTAFNTB
SCHEMBL7907301 0.94 FNTA (0.65) FNTAFNTB
SCHEMBL7907005 0.94 FNTA (0.66) FNTAFNTB
SCHEMBL7905488 0.94 FNTA (0.64) FNTAFNTB
SCHEMBL7907000 0.94 FNTA (0.66) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed