SCHEMBL7905142

SCHEMBL7905142

CCCCC(Cc1ccccc1Cl)OCc1ccc(C(=O)NC(CCSC)C(=O)O)c(-c2ccccc2C)c1.[LiH]

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 9/20 0.57
FNTB P49356 9/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7905148 1.00 FNTA (0.57) FNTAFNTB
SCHEMBL7910454 0.99 FNTA (0.57) FNTAFNTB
SCHEMBL7910451 0.99 FNTA (0.57) FNTAFNTB
SCHEMBL7904989 0.91 FNTA (0.64) FNTAFNTB
SCHEMBL7904981 0.91 FNTA (0.64) FNTAFNTB
SCHEMBL8587328 0.90 FNTA (0.65) FNTAFNTB
SCHEMBL8587329 0.90 FNTA (0.65) FNTAFNTB
SCHEMBL7910279 0.85 FNTA (0.64) FNTAFNTB
SCHEMBL7910270 0.85 FNTA (0.64) FNTAFNTB
SCHEMBL7906514 0.85 FNTA (0.64) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed