SCHEMBL7905151

SCHEMBL7905151

COc1ccc(COCc2ccc(C(=O)N[C@@H](CCSC)C(=O)O)c(-c3ccccc3C)c2)cc1.[LiH]

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 11/20 0.68
FNTB P49356 11/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7905143 1.00 FNTA (0.68) FNTAFNTB
SCHEMBL7905434 0.99 FNTA (0.69) FNTAFNTB
SCHEMBL7905438 0.99 FNTA (0.69) FNTAFNTB
SCHEMBL7907140 0.94 FNTA (0.70) FNTAFNTB
SCHEMBL7907146 0.94 FNTA (0.70) FNTAFNTB
SCHEMBL7906575 0.93 FNTA (0.68) FNTAFNTB
SCHEMBL7906568 0.93 FNTA (0.68) FNTAFNTB
SCHEMBL7903906 0.93 FNTA (0.71) FNTAFNTB
SCHEMBL7903903 0.93 FNTA (0.71) FNTAFNTB
SCHEMBL7904131 0.93 FNTA (0.65) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed