Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8182037 | 1.00 | — | — | |
| Bromide SCHEMBL8067592 | 1.00 | — | — | |
| SCHEMBL1036780 | 0.97 | — | — | |
| SCHEMBL5705282 | 0.97 | — | — | |
| SCHEMBL6982780 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL7038865 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL5814685 | 0.95 | — | — | |
| SCHEMBL19743910 | 0.82 | — | — | |
| SCHEMBL1432714 | 0.80 | — | — | |
| SCHEMBL20729465 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197761-B1 | ANTIINFLAMMATORY, ANTALLERGEN AGENTS | GLAXO WELLCOME INC. | 2001-03-06 | — | — | US | disclosed |
| EP-0876392-B1 | LACTONE DERIVATIVES OF 17.BETA.-CARBOXY, CARBOTHIO AND AMIDE ANDROSTANE DERIVATIVES | GLAXO GROUP LTD (GB) | 2000-07-05 | — | — | EP | disclosed |