Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899749 | 0.92 | ESR1 (0.40) | ESR1SRD5A2CYP3A4KDM4EGAA | |
| SCHEMBL7899738 | 0.86 | ESR1 (0.47) | ESR1KDM4EVDR | |
| SCHEMBL7907551 | 0.85 | CYP3A4 (0.38) | ESR1SRD5A2CYP3A4KDM4EGAA | |
| SCHEMBL7907594 | 0.82 | S1PR1 (0.31) | GAAKMT2AHSD17B10 | |
| SCHEMBL7906103 | 0.79 | ESR1 (0.38) | ESR1SRD5A2CYP3A4KDM4EGAA | |
| SCHEMBL7912746 | 0.79 | ESR1 (0.53) | ESR1ESR2VDR | |
| SCHEMBL7909209 | 0.77 | SMN1; SMN2 (0.50) | CYP3A4KDM4EGAAKMT2AUSP2 | |
| SCHEMBL7912756 | 0.77 | ESR1 (0.38) | ESR1SRD5A2CYP3A4KDM4EGAA | |
| SCHEMBL7907547 | 0.76 | ESR1 (0.49) | ESR1KDM4EVDR | |
| SCHEMBL17116340 | 0.74 | CYP3A4 (0.57) | ESR1CYP3A4KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187493-B1 | CHARGE GENERATING MATERIAL AND ELECTRON TRANSFER MATERIAL UNIFORMLY DISPERSED WITHIN COMPATIBLE POLYESTER BINDER; PHOTOSENSITIVITY, WEAR RESISTANCE, ADHESION TO ELECTROCONDUCTIVE SUBSTRATE | KYOCERA MITA CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0738934-A2 | Electrophotosensitive material | MITA INDUSTRIAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |