Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290980 | 1.00 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL2291173 | 1.00 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL2288534 | 0.98 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL11296489 | 0.97 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL3929627 | 0.97 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL2296519 | 0.94 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL2296156 | 0.94 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL7919748 | 0.94 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL27478078 | 0.94 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL7919739 | 0.94 | TSHR (0.51) | NPC1RAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207739-B1 | Polyamide acid composition containing metal, polyimide film, flexible printed wiring board and method for producing them | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI (JP) | 2001-03-27 | — | — | US | disclosed |