SCHEMBL7906151

SCHEMBL7906151

CO[Si](CC[Si](C)(C)O[Si](C)(C)CCC1CCC2OC2C1)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20085422 0.93 PTGS1 (0.34) PTGS1PTGS2
SCHEMBL19622363 0.89 PTGS1 (0.36) PTGS1PTGS2
SCHEMBL1079186 0.89 PTGS1 (0.36) PTGS1PTGS2
SCHEMBL16020793 0.88 PTGS1 (0.35) PTGS1PTGS2
SCHEMBL4878967 0.88 PTGS1 (0.35) PTGS1PTGS2
SCHEMBL20478201 0.88 PTGS1 (0.35) PTGS1PTGS2
SCHEMBL48081 0.88 PTGS1 (0.35) PTGS1PTGS2
SCHEMBL16342441 0.86 PTGS1 (0.33) PTGS1PTGS2
SCHEMBL2300512 0.86 PTGS1 (0.34) PTGS1PTGS2
SCHEMBL28274253 0.86 PTGS1 (0.34) PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6210790-B1 TRANSPARENCY, HARDNESS, ABRASION-RESISTANCE RENSSELAER POLYTECHNIC INSTITUTE 2001-04-03 US claimed
US-6210790-B1 TRANSPARENCY, HARDNESS, ABRASION-RESISTANCE RENSSELAER POLYTECHNIC INSTITUTE 2001-04-03 US disclosed