⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897876 | 0.84 | FNTA (0.56) | — | |
| SCHEMBL7897879 | 0.84 | FNTA (0.56) | — | |
| SCHEMBL7904108 | 0.79 | FNTA (0.41) | — | |
| SCHEMBL7897860 | 0.74 | FNTA (0.57) | — | |
| SCHEMBL7897857 | 0.74 | FNTA (0.57) | — | |
| SCHEMBL6625288 | 0.73 | FNTA (0.42) | — | |
| SCHEMBL7897805 | 0.73 | FNTA (0.57) | — | |
| Lithium SCHEMBL7897810 | 0.73 | FNTA (0.57) | — | |
| SCHEMBL7918444 | 0.72 | FNTA (0.40) | — | |
| SCHEMBL7906200 | 0.72 | FNTA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |