Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.48 |
| ▸ | PPARG | P37231 | 16/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911555 | 0.88 | PPARA (0.50) | PPARAPPARGPPARD | |
| SCHEMBL204655 | 0.80 | SMN1; SMN2 (0.48) | PPARAPPARGPPARD | |
| SCHEMBL4389491 | 0.77 | HRH3 (0.61) | PPARAPPARGPPARD | |
| SCHEMBL7898762 | 0.76 | PPARG (0.62) | PPARAPPARGPPARD | |
| SCHEMBL7722459 | 0.76 | HRH3 (0.46) | PPARAPPARGPPARD | |
| SCHEMBL7907791 | 0.75 | PREP (0.40) | PPARAPPARGPREP | |
| SCHEMBL3843622 | 0.72 | PREP (0.44) | PPARAPREP | |
| SCHEMBL201829 | 0.72 | TARBP2 (0.53) | PPARAPPARG | |
| SCHEMBL23491348 | 0.71 | PREP (0.57) | PREP | |
| SCHEMBL5855804 | 0.71 | PPARG (0.53) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |