Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906787 | 0.97 | GRIN2D (0.36) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7907819 | 0.84 | GRIN2D (0.31) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL1721732 | 0.82 | PDE9A (0.40) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7908900 | 0.82 | PDE9A (0.35) | CYP11B2SCN9A | |
| SCHEMBL12044760 | 0.80 | PDE9A (0.34) | — | |
| SCHEMBL7909964 | 0.79 | PDE9A (0.32) | — | |
| SCHEMBL7909054 | 0.79 | PDE9A (0.40) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL1721608 | 0.77 | PDE9A (0.34) | — | |
| SCHEMBL7899049 | 0.77 | — | — | |
| SCHEMBL1721605 | 0.76 | AVPR2 (0.40) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101230-A1 | QUINOXALINE COMPOUNDS | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |