Sugi Predict

Sugi Predict / Compounds / Lithium

Lithium

Lithium

SCHEMBL7906380

CCSCC(CC1CCCCC1)OCc1ccc(C(=O)N[C@@H](CCSC)C(=O)O)c(-c2ccccc2C)c1.[Li]

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 2/20 0.61
▸ FNTB P49356 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7903881 0.99 FNTA (0.62) FNTAFNTB
SCHEMBL7903886 0.99 FNTA (0.62) FNTAFNTB
SCHEMBL7906377 0.99 FNTA (0.61) FNTAFNTB
SCHEMBL8587153 0.94 FNTA (0.63) FNTAFNTB
SCHEMBL7905861 0.94 FNTA (0.63) FNTAFNTB
SCHEMBL7905868 0.94 FNTA (0.63) FNTAFNTB
SCHEMBL7910205 0.93 FNTA (0.56) FNTAFNTB
SCHEMBL7907265 0.93 FNTA (0.65) FNTAFNTB
SCHEMBL7907268 0.93 FNTA (0.65) FNTAFNTB
SCHEMBL7906923 0.92 FNTA (0.64) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 — — US disclosed