Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920252 | 1.00 | GAA (0.65) | GAAMAPTKDM4ETSHRPRSS1 | |
| SCHEMBL11341850 | 1.00 | GAA (0.65) | GAAMAPTKDM4ETSHRPRSS1 | |
| SCHEMBL25193781 | 0.98 | GAA (0.67) | GAAMAPTKDM4ETSHRPRSS1 | |
| SCHEMBL30336546 | 0.98 | GAA (0.67) | GAAMAPTKDM4ETSHRPRSS1 | |
| SCHEMBL10188105 | 0.93 | GAA (0.69) | GAAMAPTKDM4ETSHRPRSS1 | |
| SCHEMBL22502366 | 0.92 | GAA (0.57) | GAAMAPTKDM4ETSHRPRSS1 | |
| SCHEMBL9168790 | 0.91 | TSHR (0.57) | GAAMAPTKDM4ETSHRHTT | |
| SCHEMBL1608893 | 0.91 | TSHR (0.57) | GAAMAPTKDM4ETSHRHTT | |
| SCHEMBL3278460 | 0.91 | TSHR (0.57) | GAAMAPTKDM4ETSHRHTT | |
| SCHEMBL7045133 | 0.91 | TSHR (0.57) | GAAMAPTKDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214990-B1 | 2,9-BIS(4-METHOXYBENZOYLOXY),3,10-DIMETHOXY,6,13-DICHLORO -PHENODIOXAZINE, FOR EXAMPLE; DYE HAS NARROW LIGHT ABORPTION BAND AND HIGH DICHROIC RATIO | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |