Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907495 | 0.97 | CNR1 (0.35) | CNR1EPHX2ALDH1A1CNR2CYP46A1 | |
| SCHEMBL7906059 | 0.87 | CNR1 (0.35) | CNR1 | |
| SCHEMBL476268 | 0.87 | CNR1 (0.41) | CNR1EPHX2CNR2CYP46A1 | |
| SCHEMBL7906061 | 0.86 | CNR1 (0.37) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL2682596 | 0.86 | CNR1 (0.41) | CNR1EPHX2CNR2CYP46A1 | |
| SCHEMBL2682864 | 0.84 | CNR1 (0.42) | CNR1EPHX2ALDH1A1CNR2CYP46A1 | |
| SCHEMBL476384 | 0.81 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL2683112 | 0.80 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL2681835 | 0.79 | CNR1 (0.39) | CNR1EPHX2CNR2CYP46A1 | |
| SCHEMBL476350 | 0.78 | CNR1 (0.46) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010109150-A1 | DERIVATIVES OF 3-ALKOXY-4,5-DIARYLTHIOPHENE-2-CARBOXAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-09-30 | — | — | WO | disclosed |