SCHEMBL7906920

SCHEMBL7906920

COC(c1ccc(C(=O)NC(CCSC)C(=O)O)c(-c2ccccc2C)c1)c1ccco1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 13/20 0.55
FNTB P49356 13/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8588845 0.89 FNTA (0.61) FNTAFNTB
SCHEMBL8639666 0.89 FNTA (0.56) FNTAFNTB
SCHEMBL7903706 0.88 FNTA (0.60) FNTAFNTB
SCHEMBL7906912 0.88 FNTA (0.56) FNTAFNTB
SCHEMBL8588390 0.88 FNTA (0.51) FNTAFNTB
Lithium SCHEMBL7906915 0.88 FNTA (0.56) FNTAFNTB
SCHEMBL8587323 0.88 FNTA (0.55) FNTAFNTB
SCHEMBL7897459 0.87 FNTA (0.55) FNTAFNTB
SCHEMBL7903947 0.87 FNTA (0.55) FNTAFNTB
SCHEMBL8590865 0.87 FNTA (0.59) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998050031-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 WO claimed
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed