SCHEMBL7907116

SCHEMBL7907116

COCC(CC1CCCCC1)OCc1ccc(C(=O)NC(CCSC)C(=O)OC)c(-c2ccccc2C)c1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.58
FNTB P49356 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7907122 1.00 FNTA (0.58) FNTAFNTB
SCHEMBL7896539 0.95 FNTA (0.58) FNTAFNTB
SCHEMBL7896533 0.95 FNTA (0.58) FNTAFNTB
SCHEMBL7906555 0.94 FNTA (0.56) FNTAFNTB
SCHEMBL7906550 0.94 FNTA (0.56) FNTAFNTB
SCHEMBL7897773 0.94 FNTA (0.61) FNTAFNTB
SCHEMBL7897777 0.94 FNTA (0.61) FNTAFNTB
SCHEMBL7897676 0.94 FNTA (0.56) FNTAFNTB
SCHEMBL7903682 0.94 FNTA (0.58) FNTAFNTB
SCHEMBL7903688 0.94 FNTA (0.58) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed