SCHEMBL7907154

SCHEMBL7907154

CCCCC[C@H]1CC[C@H](C(=O)Oc2ccc(OCC)c(F)c2F)CC1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.42
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.39
HTT P42858 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
GLA P06280 1/20 0.37
CCR2 P41597 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7907158 1.00 HPGD (0.42) HPGDGAAMAPTPKMHTT
SCHEMBL9562428 0.99 HPGD (0.41) HPGDGAAMAPTPKMHTT
SCHEMBL9562433 0.99 HPGD (0.41) HPGDGAAMAPTPKMHTT
SCHEMBL9405908 0.96 HPGD (0.40) HPGDGAAMAPTPKMHTT
SCHEMBL9405910 0.96 HPGD (0.40) HPGDGAAMAPTPKMHTT
SCHEMBL7908250 0.96 HPGD (0.43) HPGDGAAMAPTHTTMEN1
SCHEMBL7908246 0.96 HPGD (0.43) HPGDGAAMAPTHTTMEN1
SCHEMBL9405978 0.95 HPGD (0.39) HPGDGAAMAPTPKMHTT
SCHEMBL9405887 0.95 HPGD (0.39) HPGDGAAMAPTPKMHTT
SCHEMBL9406622 0.95 HPGD (0.39) HPGDGAAMAPTPKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5248447-A 2,3-difluorohydroquinone derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-09-28 US claimed
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
EP-0438547-B2 SUPER-TWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1999-07-07 EP disclosed
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US disclosed
EP-0494368-B1 Supertwist liquid crystal display MERCK PATENT GMBH (DE) 1999-01-20 EP disclosed
EP-0481293-B1 Supertwist liquid crystal display MERCK PATENT GMBH (DE) 1996-06-05 EP disclosed
US-5387369-A With specified mixture of components; short switching times MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-07 US disclosed
EP-0438547-B1 SUPER-TWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1994-12-14 EP disclosed
US-5279764-A Dihalogenobenzene derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-01-18 US disclosed
US-5248447-A 2,3-difluorohydroquinone derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-09-28 US disclosed
US-5143642-A Thiadiazoles MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-09-01 US disclosed
EP-0494368-A2 Supertwist liquid crystal display MERCK PATENT GmbH (DE) 1992-07-15 EP disclosed
EP-0481293-A2 Supertwist liquid crystal display MERCK PATENT GmbH (DE) 1992-04-22 EP disclosed
EP-0438547-A1 SUPER-TWIST LIQUID CRYSTAL DISPLAY. MERCK PATENT GMBH (DE) 1991-07-31 EP disclosed
US-5004753-A Novel carboxylic acid esters, method for their production and insecticides containing them as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-04-02 US disclosed
WO-1991000898-A1 SUPER-TWIST LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-01-24 WO disclosed
EP-0373186-A1 DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE MERCK PATENT GmbH (DE) 1990-06-20 EP disclosed
WO-1989008637-A1 DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed
EP-0332007-A1 Derivatives of 2,3-difluorohydroquinone MERCK PATENT GmbH (DE) 1989-09-13 EP disclosed
EP-0291045-A2 Novel carboxylic acid esters, method for their production and insecticides containing them as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-17 EP disclosed