SCHEMBL7907210

SCHEMBL7907210

CSCCC(NC(=O)c1ccc(C(OCC2COC(C)(C)O2)OC(C)CC2CCCCC2)cc1-c1ccccc1C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.49
FNTB P49356 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7910291 0.99 FNTA (0.48) FNTAFNTB
SCHEMBL7897860 0.85 FNTA (0.57) FNTAFNTB
SCHEMBL7897857 0.85 FNTA (0.57) FNTAFNTB
Lithium SCHEMBL7897810 0.85 FNTA (0.57) FNTAFNTB
SCHEMBL7897805 0.85 FNTA (0.57) FNTAFNTB
SCHEMBL7910186 0.84 FNTA (0.52) FNTAFNTB
SCHEMBL7910184 0.84 FNTA (0.52) FNTAFNTB
SCHEMBL7897879 0.84 FNTA (0.56) FNTAFNTB
SCHEMBL7897876 0.84 FNTA (0.56) FNTAFNTB
SCHEMBL8589925 0.84 FNTA (0.56) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed