SCHEMBL7907264

SCHEMBL7907264

CCCCC(C)OC(c1ccc(C(=O)N[C@@H](CCSC)C(=O)OC)c(-c2ccccc2C)c1)C1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 4/20 0.52
FNTB P49356 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7910664 0.93 FNTA (0.59) FNTAFNTB
Lithium SCHEMBL7905133 0.93 FNTA (0.59) FNTAFNTB
SCHEMBL7907260 0.88 FNTA (0.52) FNTAFNTB
SCHEMBL7869063 0.84 FNTA (0.49) FNTAFNTB
SCHEMBL628946 0.83 FNTA (0.58) FNTAFNTB
SCHEMBL7906871 0.83 FNTA (0.53) FNTAFNTB
SCHEMBL628593 0.83 FNTA (0.50) FNTAFNTB
SCHEMBL7903618 0.83 FNTA (0.50) FNTAFNTB
SCHEMBL7903962 0.82 FNTA (0.60) FNTAFNTB
SCHEMBL7910659 0.82 FNTA (0.59) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed