Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907471 | 1.00 | SMPD1 (0.52) | SMPD1FFAR1MAOB | |
| SCHEMBL7900916 | 0.93 | MAOB (0.54) | SMPD1FFAR1MAOB | |
| SCHEMBL7901041 | 0.93 | MAOB (0.54) | SMPD1FFAR1MAOB | |
| SCHEMBL7900921 | 0.93 | MAOB (0.54) | SMPD1FFAR1MAOB | |
| SCHEMBL7901022 | 0.92 | MRGPRX4 (0.52) | FFAR1MAOB | |
| SCHEMBL7901026 | 0.92 | MRGPRX4 (0.52) | FFAR1MAOB | |
| SCHEMBL8547554 | 0.91 | SMPD1 (0.53) | SMPD1MAOB | |
| SCHEMBL7909065 | 0.91 | FFAR1 (0.47) | FFAR1 | |
| SCHEMBL7909072 | 0.91 | FFAR1 (0.47) | FFAR1 | |
| SCHEMBL7907974 | 0.90 | NR4A2 (0.56) | SMPD1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | claimed |
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |