SCHEMBL7907565

SCHEMBL7907565

OCCOc1ccc(C2(c3ccc(OCCO)c(Cc4ccccc4)c3)CCCCC2)cc1Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 10/20 0.42
DRD1 P21728 4/20 0.42
DRD4 P21917 4/20 0.42
DRD5 P21918 4/20 0.42
DRD3 P35462 3/20 0.42
DRD2 P14416 3/20 0.42
SLC6A9 P48067 1/20 0.41
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PPARA Q07869 1/20 0.38
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
THRA P10827 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5500435 0.85 HRH1 (0.36) HRH1DRD1DRD4DRD5DRD3
SCHEMBL7912738 0.82 PPARA (0.46) PPARATSHRLMNA
SCHEMBL7912709 0.82 C5AR1 (0.44) SLC6A9SMN1; SMN2PPARATP53LMNA
SCHEMBL5495930 0.82 PPARA (0.46) PPARATSHRLMNA
SCHEMBL7906118 0.82 PPARA (0.46) PPARATSHRLMNA
SCHEMBL7909157 0.80 PPARA (0.44) PPARATSHRLMNA
SCHEMBL7909253 0.80 PPARA (0.42) PPARATSHRLMNA
SCHEMBL7899709 0.80 PPARA (0.42) PPARATSHRLMNA
SCHEMBL5500330 0.80 PPARA (0.42) PPARATSHRLMNA
SCHEMBL7912767 0.79 PPARA (0.41) PPARAL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6187493-B1 CHARGE GENERATING MATERIAL AND ELECTRON TRANSFER MATERIAL UNIFORMLY DISPERSED WITHIN COMPATIBLE POLYESTER BINDER; PHOTOSENSITIVITY, WEAR RESISTANCE, ADHESION TO ELECTROCONDUCTIVE SUBSTRATE KYOCERA MITA CORPORATION (JP) 2001-02-13 US disclosed
EP-0738934-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1996-10-23 EP disclosed