Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.64 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.64 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.64 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.64 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.64 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10237219 | 0.90 | CYP2C9 (0.66) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10237217 | 0.90 | CYP2C9 (0.66) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10236641 | 0.90 | CYP2C9 (0.66) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10236646 | 0.90 | CYP2C9 (0.66) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL722640 | 0.90 | CYP2C9 (0.66) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10237278 | 0.90 | CYP2C9 (0.65) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10237260 | 0.90 | CYP2C9 (0.68) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10237276 | 0.90 | CYP2C9 (0.65) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10237261 | 0.90 | CYP2C9 (0.68) | CYP2C9PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10237231 | 0.86 | CYP2C9 (0.69) | CYP2C9PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010098487-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |