SCHEMBL7908233

SCHEMBL7908233

Cc1cc(C)cc(-c2[nH]c3ccc(Nc4ncc(-c5ccccc5)o4)cc3c2CCNCCCCc2ccc(NS(C)(=O)=O)cc2)c1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7908822 0.84 GNRHR (0.48) GNRHR
SCHEMBL7905608 0.80 GNRHR (0.82) GNRHR
SCHEMBL7908709 0.80 GNRHR (0.70) GNRHR
SCHEMBL7908807 0.77 GNRHR (0.75) GNRHR
SCHEMBL7899346 0.77 GNRHR (0.68) GNRHR
SCHEMBL8693238 0.76 GNRHR (0.73) GNRHR
SCHEMBL8690502 0.75 GNRHR (0.76) GNRHR
SCHEMBL7997217 0.75 GNRHR (0.72) GNRHR
SCHEMBL7912405 0.75
SCHEMBL7905624 0.75 GNRHR (0.71) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197975-B1 7-AZABICYCLO(2.2.1)HEPTANE-7-CARBONYL-SUBSTITUTED 2-PHENYLINDOLE DERIVATIVES; SEXUAL DISORDERS; ANTICARCINOGENIC AGENTS MERCK & CO. , INC. 2001-03-06 US disclosed