SCHEMBL7908457

SCHEMBL7908457

O=C1c2ccccc2C(=O)c2c(O)c(Cl)c(Cl)c(O)c21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.59
KMT2A Q03164 7/20 0.59
MAOA P21397 6/20 0.59
MAPT P10636 5/20 0.59
HPGD P15428 4/20 0.59
MAPK1 P28482 4/20 0.59
ALDH1A1 P00352 3/20 0.59
CYP3A4 P08684 3/20 0.59
ALOX15 P16050 3/20 0.59
ALOX12 P18054 3/20 0.59
HSD17B10 Q99714 3/20 0.59
DAPK1 P53355 3/20 0.59
KDM4E B2RXH2 3/20 0.59
RECQL P46063 3/20 0.59
CYP1B1 Q16678 2/20 0.59
BRCA1 P38398 2/20 0.59
TTR P02766 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
CYP1A1 P04798 1/20 0.59
HSPD1 P10809 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29883748 1.00 MEN1 (0.59) MEN1KMT2AMAOAMAPTHPGD
SCHEMBL11746573 0.91 MEN1 (0.55) MEN1KMT2AMAOAMAPTHPGD
SCHEMBL11884746 0.90 MEN1 (0.53) MEN1KMT2AMAOAMAPTHPGD
SCHEMBL12691769 0.89 DAPK1 (0.57) MEN1KMT2AMAOAMAPTHPGD
SCHEMBL899150 0.85 MEN1 (0.68) MEN1KMT2AMAOAMAPTHPGD
SCHEMBL8581315 0.81 MEN1 (0.63) MEN1KMT2AMAOAMAPTHPGD
SCHEMBL29007246 0.81 MEN1 (0.49) MEN1KMT2AMAOAMAPTHPGD
Dichlon SCHEMBL11584433 0.80 IDO1 (0.70) MEN1KMT2AMAOAMAPTHPGD
SCHEMBL11851977 0.79 MEN1 (0.56) MEN1KMT2AMAOAMAPTHPGD
SCHEMBL9296456 0.79 MEN1 (0.56) MEN1KMT2AMAOAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116515166-A Colorant for resin coloring and preparation method thereof 双乐颜料股份有限公司 2023-08-01 CN claimed
CN-115117467-A Acid water system all-organic symmetrical battery based on dihydroxynaphthalene dione derivative 常州大学 2022-09-27 CN claimed
CN-116515166-A Colorant for resin coloring and preparation method thereof 双乐颜料股份有限公司 2023-08-01 CN disclosed
CN-115117467-A Acid water system all-organic symmetrical battery based on dihydroxynaphthalene dione derivative 常州大学 2022-09-27 CN disclosed
US-6191152-B1 CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS EGIS GYÓGYSZERGYAR RT. (HU) 2001-02-20 US disclosed
US-4645626-A Process for the production of quinizarine derivatives which are disubstituted in the 5- and 8-positions by hydroxyl or chlorine CIBA-GEIGY AG (CH) 1987-02-24 US disclosed
US-4645626-A Process for the production of quinizarine derivatives which are disubstituted in the 5- and 8-positions by hydroxyl or chlorine CIBA-GEIGY AG (CH) 1987-02-24 US disclosed