SCHEMBL7908505

SCHEMBL7908505

CSCCC(NC(=O)c1ccc(C(N)C(CO)CC2CCCCC2)cc1-c1ccccc1C)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.58
FNTB P49356 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6625521 1.00 FNTA (0.58) FNTAFNTB
SCHEMBL628618 0.95 FNTA (0.59) FNTAFNTB
SCHEMBL7870229 0.94 FNTA (0.59) FNTAFNTB
SCHEMBL629726 0.93 FNTA (0.63) FNTAFNTB
SCHEMBL7868985 0.93 FNTA (0.56) FNTAFNTB
SCHEMBL7870168 0.92 FNTA (0.62) FNTAFNTB
SCHEMBL2944388 0.92 FNTA (0.57) FNTAFNTB
SCHEMBL628491 0.91 FNTA (0.59) FNTAFNTB
SCHEMBL7897649 0.91 FNTA (0.56) FNTAFNTB
SCHEMBL629279 0.91 FNTA (0.56) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6221865-B1 INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. UNIVERSITY OF PITTSBURGH 2001-04-24 US disclosed