Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.49 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474821 | 0.92 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2SRCTLR2 | |
| SCHEMBL26731687 | 0.88 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2SRCTLR2 | |
| SCHEMBL7775011 | 0.86 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2SRCTLR2 | |
| SCHEMBL636533 | 0.86 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2SRCTLR2 | |
| SCHEMBL637742 | 0.86 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2SRCTLR2 | |
| SCHEMBL636327 | 0.85 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2SRCTLR2 | |
| SCHEMBL637169 | 0.84 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2SRCTLR2 | |
| SCHEMBL637615 | 0.84 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2SRCTLR2 | |
| SCHEMBL2821669 | 0.84 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2SRCTLR2 | |
| SCHEMBL3062573 | 0.84 | SMN1; SMN2 (0.77) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119409667-A | Dithioacetal derivative containing sulfonyl piperazine unit, and preparation method and application thereof | 贵州大学 | 2025-02-11 | — | — | CN | disclosed |
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |
| EP-0958294-A1 | 2-(1,2,4-TRIAZOLE-1-YL)-1,3,4-THIADIAZOLE DERIVATIVES HAVING AN EFFECT ON THE C.N.S. AND THE HEART | EGIS GYOGYSZERGYAR (HU) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998030561-A1 | 2-(1,2,4-TRIAZOLE-1-YL)-1,3,4-THIADIAZOLE DERIVATIVES HAVING AN EFFECT ON THE C.N.S. AND THE HEART | EGIS Gyógyszergyár Rt. (HU) | 1998-07-16 | — | — | WO | disclosed |