Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516219 | 0.81 | NPC1 (0.56) | NPC1GAAALOX5MAPTSMN1; SMN2 | |
| SCHEMBL27764131 | 0.81 | NPC1 (0.56) | NPC1GAAALOX5SMN1; SMN2CYP3A4 | |
| SCHEMBL9733791 | 0.81 | NPC1 (0.55) | NPC1GAAALOX5MAPTNPSR1 | |
| SCHEMBL4420391 | 0.81 | ESR1 (0.58) | NPC1ALOX5SMN1; SMN2CYP3A4PTPN2 | |
| SCHEMBL11358519 | 0.80 | ESR1 (0.62) | NPC1ALOX5SMN1; SMN2CYP3A4L3MBTL1 | |
| SCHEMBL3455024 | 0.79 | NPC1 (0.51) | NPC1ALOX5MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL3310239 | 0.79 | NPC1 (0.51) | NPC1ALOX5MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL1114367 | 0.79 | NPC1 (0.79) | NPC1ALOX5MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL7512104 | 0.79 | NPC1 (0.54) | NPC1ALOX5MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9676771 | 0.79 | ESR1 (0.68) | NPC1ALOX5MAPTALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200831-B1 | HEAT-CURING A COATING OF A POLYAMIC ACID BASED ON A TETRACARBOXYLIC ACID AND A DIAMINE CONTAINNG AN ACTIVE OXYGEN OR NITROGEN FUNCTIONAL GROUP; SEALING THE EXTERNAL TERMINALS WITH A RESIN, E.G. AN EPOXIDE | HITACHI, LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| US-6087006-A | SEMICONDUCTOR DEVICE HAVING SURFACE-PROTECTING FILM COMPRISING POLYIMIDE OBTAINED BY HEAT-CURING PRECURSOR HAVING POLAR SUBSTITUENTS AS THE SIDE CHAINS | HITACHI, LTD. (JP) | 2000-07-11 | — | — | US | disclosed |