Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | CPA3 | P15088 | 3/20 | 0.51 |
| ▸ | CPA1 | P15085 | 6/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907545 | 1.00 | CYP1A2 (0.57) | CYP1A2EPHX1CPA3CPA1FOLH1 | |
| SCHEMBL4020655 | 1.00 | CYP1A2 (0.57) | CYP1A2EPHX1CPA3CPA1FOLH1 | |
| SCHEMBL28179819 | 0.89 | FOLH1 (0.54) | CYP1A2EPHX1CPA3CPA1FOLH1 | |
| SCHEMBL5052372 | 0.86 | CYP1A2 (0.68) | CYP1A2EPHX1CPA3CPA1FOLH1 | |
| SCHEMBL3044591 | 0.85 | CYP1A2 (0.57) | CYP1A2EPHX1CPA3CPA1FOLH1 | |
| SCHEMBL27417767 | 0.85 | CYP1A2 (0.57) | CYP1A2EPHX1CPA3CPA1FOLH1 | |
| SCHEMBL7303315 | 0.85 | CYP1A2 (0.73) | CYP1A2CPA3CPA1FOLH1SLC1A3 | |
| SCHEMBL7301792 | 0.85 | CYP1A2 (0.73) | CYP1A2CPA3CPA1FOLH1SLC1A3 | |
| SCHEMBL7667156 | 0.85 | CYP1A2 (0.73) | CYP1A2CPA3CPA1FOLH1SLC1A3 | |
| SCHEMBL1059561 | 0.85 | CYP1A2 (0.61) | CYP1A2EPHX1CPA3CPA1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207862-B1 | PRECURSORS ARE CHIRAL 4-HYDROXYCARBOXAMIDES, 4-HYDROXYHYDROXAMIC ACIDS, OR 4-HYDROXYHYDRAZIDES PRODUCED FROM GAMMA-LACTONES, WHICH IN TURN ARE DERIVED FROM 1,4-DIOLS BY STEREOSELECTIVE OXIDATION, | BIOCATALYTICS, INC. | 2001-03-27 | — | — | US | disclosed |
| WO-1999032649-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL 1,3-AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| US-5916786-A | Method for the production of chiral 1,3-aminoalcohols | BIOCATALYTICS, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5693650-A | TREATING ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |