SCHEMBL7908786

SCHEMBL7908786

Cc1c(F)cc(C(F)c2c(C3CCCC3)nc3c(c2-c2ccc(F)cc2)C(O[Si](C)(C)C(C)(C)C)CC(C)(C)C3)c(F)c1F

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7154159 0.93 CETP (0.51) CETP
SCHEMBL6527592 0.84 CETP (0.57) CETP
SCHEMBL993371 0.83 CETP (0.74) CETP
SCHEMBL7154158 0.82 CETP (0.61) CETP
SCHEMBL6477347 0.79 CETP (0.49) CETP
SCHEMBL6475766 0.79 CETP (0.62) CETP
SCHEMBL992738 0.78 CETP (0.64) CETP
SCHEMBL7911860 0.77 CETP (0.38) CETP
SCHEMBL6475752 0.76 CETP (0.47) CETP
SCHEMBL662849 0.74 CETP (0.51) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6207671-B1 FOR TREATMENT OF HYPERTIPOPROTEINAEMIA, ARTERIOSCLEROSIS DYSLIPIDAEMIA BAYER AKTIENGESELLSCHAFT (DE) 2001-03-27 US disclosed