Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052403 | 0.81 | PDE10A (0.50) | PDE10AKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL1121403 | 0.79 | PDE10A (0.49) | PDE10AKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL3173439 | 0.79 | TDP1 (0.50) | PDE10AKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL26907309 | 0.79 | MEN1 (0.53) | PDE10AKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL3040780 | 0.79 | PDE10A (0.45) | PDE10AKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL11128056 | 0.78 | KMT2A (0.44) | PDE10AKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL28315154 | 0.77 | PDE10A (0.46) | PDE10AKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL13425980 | 0.76 | PDE10A (0.45) | PDE10AKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL3192292 | 0.76 | F2RL3 (0.46) | PDE10AKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL1121431 | 0.76 | TDP1 (0.49) | PDE10AKMT2AMEN1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225127-B1 | DETECTION, DETERMINATION, AND QUANTITATION OF CERTAIN ANIONS INVOLVING THE QUENCHING OF A FLUORESCENT LABEL ATTACHED TO A METALLOENZYME DUE TO FLUORESCENCE ENERGY TRANSFER TO A COLORED INHIBITOR | UNIVERSITY OF MARYLAND, BALTIMORE | 2001-05-01 | — | — | US | disclosed |
| US-6197258-B1 | DETECTOR FOR DETERMINING AQUEOUS METAL ION CONCENTRATION INCLUDING A PHOTOLUMINESCENT LABEL BOUND TO AN ANALYTE BINDING MACROMOLECULE OF HUMAN APOCARBONIC ANHYDRASE OR DERIVATIVE | UNIVERSITY OF MARYLAND, BALTIMORE | 2001-03-06 | — | — | US | disclosed |
| US-5952236-A | Enzyme-based fluorescence biosensor for chemical analysis | PATCHAN, MARCIA W. | 1999-09-14 | — | — | US | disclosed |