Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 4/20 | 0.42 |
| ▸ | MC4R | P32245 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.41 |
| ▸ | MC3R | P41968 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909281 | 1.00 | MC5R (0.42) | MC5RMC4RNPY5RMC3RMAPK1 | |
| SCHEMBL7909241 | 1.00 | MC5R (0.42) | MC5RMC4RNPY5RMC3RMAPK1 | |
| SCHEMBL7911422 | 1.00 | MC5R (0.42) | MC5RMC4RNPY5RMC3RMAPK1 | |
| SCHEMBL7911420 | 1.00 | MC5R (0.42) | MC5RMC4RNPY5RMC3RMAPK1 | |
| SCHEMBL7909244 | 1.00 | MC5R (0.42) | MC5RMC4RNPY5RMC3RMAPK1 | |
| SCHEMBL7901237 | 0.84 | MAN1B1 (0.43) | MEN1KMT2ACXCR4 | |
| SCHEMBL7901252 | 0.84 | MAN1B1 (0.43) | MEN1KMT2ACXCR4 | |
| SCHEMBL7909208 | 0.84 | MAN1B1 (0.43) | MEN1KMT2ACXCR4 | |
| SCHEMBL7162008 | 0.84 | MAN1B1 (0.43) | MEN1KMT2ACXCR4 | |
| SCHEMBL7909212 | 0.84 | MAN1B1 (0.43) | MEN1KMT2ACXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624652-B1 | Process for producing N-substituted polyhydroxy nitrogen-containing heterocycles | MONSANTO CO (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-1132370-A2 | Process for producing n-substituted polyhydroxy nitrogen-containing heterocyles | MONSANTO COMPANY (US) | 2001-09-12 | — | — | EP | disclosed |
| US-5695969-A | Process for producing N-substituted polyhydroxy nitrogen-containing heterocycles | MONSANTO COMPANY (US) | 1997-12-09 | — | — | US | disclosed |
| US-5401645-A | Process for producing n-substituted polyhydroxy nitrogen-containing heterocycles utilizing acetobacteraceae and corynebacterium | MONSANTO COMPANY (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0624652-A1 | Process for producing N-substituted polyhydroxy nitrogen-containing heterocycles | MONSANTO COMPANY (US) | 1994-11-17 | — | — | EP | disclosed |