Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | HEXB | P07686 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857472 | 0.82 | GAA (0.63) | GAAUSP2MAPTPOLB | |
| SCHEMBL1803754 | 0.78 | GAA (0.44) | GAAMAPT | |
| SCHEMBL1803885 | 0.77 | GAA (0.47) | GAAMAPTPOLB | |
| SCHEMBL33938 | 0.76 | GAA (0.45) | GAAMAPTPOLB | |
| SCHEMBL31194464 | 0.75 | MAPK1 (0.49) | GAASMN1; SMN2USP2MAPK1RECQL | |
| SCHEMBL617 | 0.74 | SMN1; SMN2 (0.61) | GAASMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL5875816 | 0.74 | SMN1; SMN2 (0.50) | GAASMN1; SMN2PDE5AMAPTTDP1 | |
| SCHEMBL3450535 | 0.74 | SMN1; SMN2 (0.50) | GAASMN1; SMN2USP2MAPTLMNA | |
| SCHEMBL1802418 | 0.72 | GAA (0.42) | GAAMAPT | |
| Hydrochloric Acid SCHEMBL7813040 | 0.72 | SMN1; SMN2 (0.60) | GAASMN1; SMN2MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204383-B1 | REACTING SIDENAFIL PRECURSOR HAVING REACTIVE FUNCTIONALIZED HYDROXY WITH METHYLAMINE,TREATING REACTION AQUEOUS MEDIUM OF ACIDIC PH CAUSING PHASE SHIFT INTO THE AQUEOUS PHASE | TORCAN CHEMICAL LTD. (CA) | 2001-03-20 | — | — | US | disclosed |