Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909681 | 1.00 | ESR2 (0.36) | ESR2SPHK1CYP2C9ESR1CYP3A4 | |
| SCHEMBL7909686 | 1.00 | ESR2 (0.36) | ESR2SPHK1CYP2C9ESR1CYP3A4 | |
| SCHEMBL7910950 | 0.88 | SPHK1 (0.37) | ESR2SPHK1CYP2C9SPHK2DGAT1 | |
| SCHEMBL7910953 | 0.88 | SPHK1 (0.37) | ESR2SPHK1CYP2C9SPHK2DGAT1 | |
| SCHEMBL7910962 | 0.88 | SPHK1 (0.37) | ESR2SPHK1CYP2C9SPHK2DGAT1 | |
| SCHEMBL7910956 | 0.88 | SPHK1 (0.37) | ESR2SPHK1CYP2C9SPHK2DGAT1 | |
| SCHEMBL7912923 | 0.88 | ESR2 (0.39) | ESR2SPHK1CYP2C9ESR1CYP3A4 | |
| SCHEMBL7912927 | 0.88 | ESR2 (0.39) | ESR2SPHK1CYP2C9ESR1CYP3A4 | |
| SCHEMBL7910755 | 0.82 | CYP2C9 (0.49) | ESR2SPHK1CYP2C9SPHK2ALDH1A1 | |
| SCHEMBL7910768 | 0.82 | CYP2C9 (0.49) | ESR2SPHK1CYP2C9SPHK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174456-B1 | STABILITY, LOW VISCOSITY AND HIGH TRANSITION TEMPERATURE OF THE ISOTROPIC PHASE | CHISSO CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0857708-A1 | LIQUID CRYSTAL COMPOUNDS HAVING SUBSTITUTED ALKYL GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1998-08-12 | — | — | EP | disclosed |